225 Results for: "crispr"

Supplier: OZ Biosciences

Optimized Cas9 Nuclease S. Pyogenes is designed for genome editing in living cells or organisms and also for in vitro digestion.

Supplier: REVVITY HEALTH SCIENCES, INC.

The DepleteX® globin depletion kit selectively removes highly expressed globin transcripts (HBA1, HBA2, HBB, and HBD) in vitro before sequencing.

Supplier: MilliporeSigma

Miracloth is an autoclavable, quick filtration material for gelatinous homogenates that is composed of rayon-polyester with an acrylic binder.

Supplier: Intact Genomics

T7 endonuclease I is useful for quantitatively estimating the nuclease-induced mutation frequency of gene edited cells and other applications.

Supplier: Revolutionary Science

9½" vertical clearance easily accommodates tall items such as 1 L flasks or beakers without removing the cover.

Supplier: Mirus Bio

TransIT-X2® dynamic delivery system is an advanced, non-liposomal polymeric system that enables high efficiency transfection of many cell types, including primary cells.

Supplier: Lucigen

E. cloni* EXPRESS BL21(DE3) Electrocompetent Cells (? 5 x 109 cfu/ug) are perfect for everyday protein expression and offer the best value available from any supplier. Packaged in two transformations per tube (DUOs) for convenience. 12 rxns.

Supplier: G-Biosciences

BX795, originally described as a moderately potent inhibitor of PDK1 (IC50=111 nM)1, is, more importantly, a dual inhibitor of TBK1 and IKKε (IC50’s=6 and 41 nM respectively)2. TBK1 and IKKε regulate the production of Type I interferons during bacterial and viral infection via phosphorylation of the transcription factor IRF3. It also inhibited of MARK, MLK, NUAK, AurB, and ERK8.3 BX795 exhibited antitumor activity in human oral squamous cell carcinoma4, pancreatic ductal adenocarcinoma5, and Glioblastoma Multiforme6. BX795 has been used to enhance lentiviral transduction efficiency in human NK cells7-9 and human primary T cells10 for CAR-T cell therapy.

Supplier: IBI Scientific

The columns and collection tubes can be used with extra reagents from previously purchased full kits.

Supplier: MilliporeSigma

Rosetta™ 2 host strains are BL21 derivatives designed to enhance the expression of eukaryotic proteins that contain codons rarely used in E. coli.

Supplier: Avantor

Bundle and save.

Supplier: EMPIRICAL BIOSCIENCE

LwCas13 is an RNA-guided ribonuclease that is naturally expressed by Leptotrichia wadei.

Supplier: MilliporeSigma

NovaBlue Competent Cells are designed for convenient and reliable plasmid transformation

Supplier: Polyplus Transfection

Dedicated buffer for jetOPTIMUS®, best-in-class DNA transfection reagent.

Supplier: G-Biosciences

Z-Competent™ E

Supplier: Lucigen

Easily synthesize high yields of RNA with this T7 RNA polymerase in vitro transcription kit.

Supplier: G-Biosciences

Potent and selective NEDD8-activating enzyme (NAE) inhibitor.1 It disrupts cullin-RING ligase-mediated protein turnover leading to apoptosis in human tumor cells. Suppresses the growth of human tumor xenografts in mice.2 Upregulates PD-L1 expression and enhances the efficacy of immune checkpoint blockade in glioblastoma.3 Modulates tumor microenviro nMent.4 Blocks the neddylation of the DNA endonuclease CtIP, which promotes HDR in Cas9- and Cpf1-mediated gene editing. Part of the CRISPY mix for increasing precise gene editing.5 Cell permeable.

Supplier: Mirus Bio

Ingenio cuvettes for the EZporator electroporation system and Lonza-Amaxa Nucleofector II/2b devices.

Supplier: Agilent Technologies

High resolution small RNA electrophoresis of fragments from 6 to 150 nt.

Supplier: Lucigen

Competent Cells include Control DNA and Recovery Medium, and are packaged as SOLOs (1 transformation per tube). Recovery Medium is also available separately. The specified transformation efficiencies are with pUC DNA.

Supplier: New England Biolabs (NEB)

Q5 High-Fidelity DNA Polymerase sets a new standard for both fidelity and robust performance.

Supplier: Abcam

Rabbit recombinant monoclonal Eph receptor B3 antibody. BSA and azide free. Suitable for WB, ICC/IF and reacts with Human, Mouse, Rat samples.

Supplier: Abcam

Rabbit Recombinant Monoclonal Factor D/CFD antibody. BSA and Azide free. Suitable for WB and reacts with Human samples.

Supplier: MilliporeSigma

Rosetta™ host strains are BL21 derivatives designed to enhance the expression of eukaryotic proteins that contain codons rarely used in E. coli.

Supplier: Abcam

Rat Monoclonal CD90/Thy1 antibody - conjugated to Cy5.5®. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication.

Supplier: Stemcell Technologies

Defined supplement for single-cell cloning of human ES and iPS cells.

Supplier: Lucigen

With Lucigen’s Endura Competent cells, you can clone unstable sequences with exceptionally reliable results

Supplier: Lucigen

Generate the highest yields of RNA quickly and easily with these T7 RNA polymerase in vitro transcription kits.

Supplier: MilliporeSigma

A common method for transformation of plasmids into E

Supplier: New England Biolabs (NEB)

The EnGen Mutation Detection Kit provides reagents for detection of on-target genome editing events.