2318 Results for: "Water Systems"

Supplier: Prosci

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Supplier: Prosci

RHOBTB1 belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system.The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate transcriptional splice variants have been characterized.

Supplier: Prosci

AKT1 is a general protein kinase capable of phosphorylating several known proteins.The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.

Supplier: VWR International

Absolute high-precision thermometers provide the exact readings necessary for critical requirements, quality control checks, and routine measurements.

Supplier: Prosci

The screening of cDNA expression libraries from human tumors with serum antibody (SEREX) has proven to be a powerful method for identifying the repertoire of tumor antigens recognized by the immune system of cancer patients, referred to as the cancer immunome. In this regard, cancer/testis (CT) antigens are of particular interest because of their immunogenicity and restricted expression patterns. Synoivial sarcomas are striking with regard to CT antigen expression, however, highly expressed in sarcoma, CT antigens do not induce frequent humoral immune responses in sarcoma patients. Sera from two patients were used to immunoscreen cDNA libraries from two synovial sarcoma cell lines and normal testis, resulting in the identification of 113 distinct antigens. Sarcoma antigen NY-SAR-91 is one of them.

Supplier: Sartorius

The Minisart® Acticosart syringe filter with chemically inert hydrophobic PTFE is suitable for venting as well as filtration of gases with a pH of 3 to 12.

Supplier: VWR International

The VWR-PH900 meter provide accurate and reliable measurements of pH, mV and temperature in any environment.

Supplier: VWR International

The VWR-M950 benchtop multi-parameter meter provides accurate and reliable measurements of pH, conductivity, ion concentration, and dissolved oxygen.

Supplier: Boster Biological Technology

Rabbit IgG polyclonal antibody for Alpha-internexin(INA) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Supplier: International Products

Micro® A07 is a powerful blend of chelating citric acid and anionic surfactants.

Supplier: Remco Products

The small bench squeegee is ideal for drying surfaces after a sanitizing process.

Supplier: JAROSLAW KUDAY

Enhance Your Lessons and Labs with Full Color Digital Images.

Supplier: BioVendor

Good for research into cardiovascular disease, Diabetology - Other Relevant Products, Energy metabolism and body weight regulation and Oncology. The immunization antigen (15.2 kDa) is a protein containing 135 AA of recombinant Human FABP5 and one extra AA, Nterminal methionine (highlighted).

Supplier: Prosci

VAX1 is a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. It may play an important role in the development of anterior ventral forebrain and visual system.This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene.

Supplier: I.W. TREMONT CO., INC.

LabExact® Grade Quartz A is a fine porosity binderless quartz (SiO₂) glass microfiber with a 99.999% efficiency in air filtration for the retention of 2.20 µm particles. This media meets or exceeds the physical, performance, and elemental requirements for EPA PM10, Ambient Air Monitoring methods.

Supplier: MP Biomedicals

Caffeine Monohydrate protects against virus induction and chemical carcinogenesis. Commonly used as a mild stimulant.

Supplier: SPEX CERTIPREP LLC

Claritas PPT® Multi-Element Standards for ICP-MS. Tuning solutions are for ICP-MS instrumentation tuning and mass calibration prior to analysis.

Supplier: HANNA INSTRUMENTS

This pH tester is sleek tester is accurate to 0.1 pH with a built-in thermometer to automatically adjust the pH reading for temperature. The waterproof design (it floats), simple operation, and replaceable electrode mean that you can rely on this meter for years. The large LCD display shows both pH and temperature readings simultaneously, while a stability indicator is displayed to alert you when a stable reading has been obtained.

Supplier: Prosci

Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito

Supplier: Lauda-Brinkmann

Our PRO units have advantages such as low filling volume combined with powerful Varioflex pump, resulting in rapid temperature change. Environment Friendly (GWP).

Supplier: Biotium

Biotium’s CellBrite™ NIR Cytoplasmic Membrane Dyes are near-infrared lipophilic carbocyanine dyes for labeling cytoplasmic membranes in live or formaldehyde-fixed cells.

Supplier: QUALITY BIOLOGICAL, INC.

TE is composed of buffering agent Tris, and chelating agent EDTA. EDTA prevents degradation of DNA and RNA by chelating magnesium (or other divalent metal ions). Together, this Tris-EDTA based solution solubilizes DNA or RNA, while protecting it from degradation.

Supplier: GENOVIS, INC MS

FabRICATOR Z Fab2 Kit consists of spin columns of FabRICATOR Z Immobilized for antibody digestion, and spin columns of CaptureSelect™* Fc resin for purification of fragments. One FabRICATOR Z spin column contains sufficient FabRICATOR Z-coupled agarose beads to process 0.5 mg mouse IgG2a and IgG3.

Supplier: Prosci

PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA,This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.

Supplier: Prosci

Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1; MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.

Supplier: Labconco

Cell logic Class II, Type B2 Biosafety Cabinets (BSCs) offer comprehensive personnel, product and environmental protection from hazardous particulates, including risk group agents requiring BSL 1-4 containment. Type B2 BSCs, sometimes referred to as 100% exhaust or total exhaust BSCs require a dedicated exhaust system and remote blower for each cabinet. Cell Logics are designed to meet the specific needs of cell research. Models feature a modified sash to accommodate a microscope and/or a temperature-controlled work area on the work surface to maintain cell viability. All models ensure the highest standard of safety and performance.

Supplier: Labconco

Interior is one piece, Type 316 stainless steel with integral work surface and drainage trough.

Supplier: PHYSITEMP INSTRUMENTS INC MS

The controller is designed around a new generation of switching power supplies which are smaller and lighter than the older BFS supplies. The supplies are overrated 100% to ensure cool operation and continuous service.

Supplier: Prosci

SLC7A1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It may also function as an ecotropic retroviral leukemia receptor.

Supplier: SPEX CERTIPREP LLC

Claritas PPT® Multi-Element Standards for ICP-MS. Tuning solutions are for ICP-MS instrumentation tuning and mass calibration prior to analysis.