1082 Results for: "Test Lead"

Supplier: Rockland Immunochemical

Leptin is a key player in the regulation of energy balance and body weight control. Once released into the circulation, it has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. It acts as an appetite-regulating factor, regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones, it increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, it induces FOS and SOCS3 expression to release anorexigenic peptides. It has a modulatory role in nutrient absorption. It reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. It acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. It may also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. It plays a pro-inflammatory role, in synergy with IL1B, by inducing NOS2 which promotes the production of IL6, IL8 and Prostaglandin E2, through a signaling pathway that involves JAK2, PI3K, MAP2K1/MEK1 and MAPK14/p38. In adaptive immunity, promotes the switch of memory T-cells towards T helper-1 cell immune responses. Increases CD4+CD25- T cells proliferation and reduces autophagy during TCR (T cell receptor) stimulation, through MTOR signaling pathway activation and BCL2 up-regulation.

Supplier: ARBOR ASSAYS MS

The Hydrogen Peroxide Colorimetric Detection Kit from Arbor Assays provides sensitive quantification of hydrogen peroxide (H₂O₂) in urine, buffer systems, and tissue culture media (TCM). The assay uses an HRP-catalyzed reaction to produce a colored product measured at 560 nm, with a detection range of 3.125 to 100 µM and sensitivity down to 1.83 µM. The simple 30-minute workflow allows rapid assessment of oxidative stress markers in biological or experimental systems. With a robust and easy-to-use protocol, this kit is ideal for research in redox biology, oxidative stress, and cell signaling pathways.

Supplier: Rockland Immunochemical

Leptin is a key player in the regulation of energy balance and body weight control. Once released into the circulation, it has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. It acts as an appetite-regulating factor, regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones, it increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, it induces FOS and SOCS3 expression to release anorexigenic peptides. It has a modulatory role in nutrient absorption. It reduces glucose absorption by enterocytes by activating PKC and leading to a sequential activation of p38, PI3K and ERK signaling pathways which exerts an inhibitory effect on glucose absorption. It acts as a growth factor on certain tissues, through the activation of different signaling pathways increases expression of genes involved in cell cycle regulation such as CCND1, via JAK2-STAT3 pathway, or VEGFA, via MAPK1/3 and PI3K-AKT1 pathways. It may also play an apoptotic role via JAK2-STAT3 pathway and up-regulation of BIRC5 expression. It plays a pro-inflammatory role, in synergy with IL1B, by inducing NOS2 which promotes the production of IL6, IL8 and Prostaglandin E2, through a signaling pathway that involves JAK2, PI3K, MAP2K1/MEK1 and MAPK14/p38. In adaptive immunity, promotes the switch of memory T-cells towards T helper-1 cell immune responses. Increases CD4+CD25- T cells proliferation and reduces autophagy during TCR (T cell receptor) stimulation, through MTOR signaling pathway activation and BCL2 up-regulation.

Supplier: Molecular Devices

Next generation SpectraMax® absorbance microplate readers.

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry the S protein of SARS-CoV-2 (GenBank: MN908947) with multiple mutations initially identified in variant of Omicron JN.1. See mutation on our website. The S has 18-aa cytoplasmic tail truncation for optimal infection.

Supplier: ARBOR ASSAYS MS

Arbor Assays' Insulin ELISA Kit enables rapid and reliable quantification of insulin in serum, plasma, and tissue culture media using a sensitive sandwich immunoassay format. This assay detects as low as 48.8 pg/ml and covers a linear detection range from 100 to 1600 pg/ml, offering high accuracy for clinical and research applications. Validated for human, bovine, and porcine insulin, the kit shows minimal cross-reactivity with rodent insulin or related peptides. With a 2 hours workflow, this kit is ideal for studies on glucose metabolism, diabetes, endocrine function, and insulin signaling.

Supplier: Electron Microscopy Sciences

Temporary adhesives that can be washed away after machining.

Supplier: Eagle Biosciences

SeroCP IgG ELISA detects IgG antibodies specific to C

Supplier: Eagle Biosciences

Fecal Giardia Iamblia Antigen ELISA is intended for qualitative detection Giardia lamblia antigen.

Supplier: ARBOR ASSAYS MS

The DNA Damage ELISA Kit from Arbor Assays quantitatively measures oxidized guanine species, including 8-OHdG, in serum, plasma, saliva, urine, feces, tissue culture media, and purified/digested DNA. This competitive immunoassay detects three forms of DNA and RNA damage products, making it ideal for evaluating oxidative stress in biological systems. With a detection limit of 50.9 pg/ml and a range of 62.5 to 8000 pg/ml, the assay is highly sensitive and suitable for diverse sample types. The kit features a 2.5 hour protocol, excellent matrix compatibility, and is ideal for research on aging, cancer, and environmental exposure.

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry the S protein of SARS-CoV-2 (GenBank: MN908947) with multiple mutations initially identified in variant of Omicron BA. The S has 18-aa cytoplasmic tail truncation for optimal infection.

Supplier: Eagle Biosciences

SeroCP Quant IgG ELISA is to determine species-specific IgG antibodies to C

Supplier: Eagle Biosciences

SeroCP IgM (RT) ELISA is to detect IgM antibodies specific to Chlamydia pneumoniae in human serum.

Supplier: Eagle Biosciences

SeroCP IgA (RT) ELISA is intended to detect IgA antibodies specific to C

Supplier: Eagle Biosciences

SeroCP IgG (RT) ELISA is intended to detect IgG aB specific to C

Supplier: Eagle Biosciences

SeroCP IgA ELISA detects IgA antibodies specific to Chlamydia pneumoniae in human serum.

Supplier: Eagle Biosciences

SeroCP Quant IgA ELISA is to determine species-specific IgA antibodies to C

Supplier: Saint Gobain Life Sciences

PharMed® BPT is designed to maintain fluid integrity during fluid transport. Transporting biocompatible fluids through a peristaltic pump limits the risk of fluid contact with any portion of the pump itself. PharMed® BPT tubing has been formulated to withstand the rigors of peristaltic pumping action while providing the biocompatible fluid surface required in sensitive applications.

Supplier: ReVacc Scientific

This kit is developed to measure the levels of human Kallikrein 3/Prostate Specific Antigen (KLK3/PSA) concentrations in cell culture supernates, serum, plasma or biological fluids.

Supplier: Thermo Fisher Scientific

TSX™ core series is engineered for reliability and designed for everyday use. When choosing a ULT freezer, protecting your valuable samples is the top priority.  The Thermo Scientific™ TSX™ core series ULT freezers are designed with this in mind, offering reliable sample protection even in the busiest laboratory environments.

Supplier: Cytiva

Blue Sepharose™ 6 Fast Flow is cibacron blue 3G coupled to Sepharose™ 6 Fast Flow. It is well established as an adsorbent for albumin and interferon at both laboratory and process scale. The blue dye binds many proteins, such as albumin, interferon, lipoproteins and blood coagulation factors. It also binds several enzymes including kinases, dehydrogenases, and most enzymes requiring adenyl-containing cofactors e.g. NAD+.

Supplier: ELGA LabWater

Ideal water system for a new start up lab. Advanced and affordable, providing tap to Type I water.

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry the S protein of SARS-CoV-2 (GenBank: MN908947) with multiple mutations initially identified in variant of Omicron BA.4/5 (BA.4 and BA.5 variants share the same Spike mutations). The S has 18-aa cytoplasmic tail truncation for optimal infection.

Supplier: Labconco

Fully-featured, energy-efficient fume hoods provide an environmentally-friendly solution to ducted fume hoods while simplifying installation.

Supplier: Labconco

Fully-featured, energy-efficient fume hood provides an environmentally-friendly solution to ducted fume hoods while simplifying installation.

Supplier: Labconco

Fully-featured, energy-efficient fume hoods provide an environmentally-friendly solution to ducted fume hoods while simplifying installation.

Supplier: Labconco

Fully-featured, energy-efficient fume hoods provide an environmentally-friendly solution to ducted fume hoods while simplifying installation. Ideal for oversized equipment.

Supplier: Labconco

Fully-featured, energy-efficient fume hoods provide an environmentally-friendly solution to ducted fume hoods while simplifying installation. Ideal for oversized equipment.

Supplier: Labconco

Fully-featured, energy-efficient fume hoods provide an environmentally-friendly solution to ducted fume hoods while simplifying installation due to their compact footprint.

Supplier: Labconco

Fully-featured, energy-efficient fume hoods provide an environmentally-friendly solution to ducted fume hoods while simplifying installation. Ideal for oversized equipment.