1082 Results for: "Test Lead"

Supplier: Antyila Scientific

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Supplier: Biosensis

TrkA is a member of the neurotrophic tyrosine kinase receptor family. It is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkA is required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). TrkA leads to cell differentiations and may play a role in specifying sensory neuron subtypes. It has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. SUBCELLULAR LOCATION: Cell membrane; single-pass type I membrane protein. Endocytosed to the endosomes upon treatment of cells with NGF. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. Both isoforms have similar biological properties. TISSUE SPECIFICITY: Isoform TrkA-II is primarily expressed in neuronal cells. Isoform TrkA-I is found in non-neuronal tissues. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutalating behaviour, mental retardation and cancer (Reference: www.uniprot.com). Reacts with human TrkA. Known to cross-react with TrkA from rat and mouse. Expected to cross-react with other mammalian species based on peptide antigen sequence similarity.

Supplier: CYTOART, INC. MS

38-1A2 is a specific antibody that binds precisely to two tandem VHH sequences of LCAR-B38M. These sequences are designed to target two epitopes of the B-cell maturation antigen (BCMA). BCMA is a protein expressed selectively by B-lineage cells, including both normal and malignant plasma cells in multiple myeloma. Ciltacabtagene autoleucel, also known as cilta-cel or Carvykti, is a gene-edited autologous CAR T-cell therapy. It utilizes LCAR and B38M to effectively recognize BCMA-positive cells.

Supplier: Anaspec

The SensoLyte® Green Glutaminyl Cyclase Activity Assay Kit provides a convenient, two-step homogeneous procedure for measuring enzyme activity from various sources using a green fluorescence substrate

Supplier: Eagle Biosciences

Anti-hu tTG IgG ELISA determines IgG autoantibodies to tissue transglutaminase in serum or plasma.

Supplier: CYTOART, INC. MS

1F5-RHC contains a specifically mutated human IgG1 Fc region which results in a reduction in binding to Fc receptors. 1F5-RHC specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells.

Supplier: CYTOART, INC. MS

The rabbit monoclonal antibody 1F5 specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells. The scFv region of 2C6 has been used to develop CD20-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: CYTOART, INC. MS

The rabbit monoclonal antibody 1F5 specifically binds to the scFv region of a CD20-specific human monoclonal antibody (mAb, clone 2C6). CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre-B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro-B cells, or normal plasma cells. The scFv region of 2C6 has been used to develop CD20-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: Bel-Art Products, a Part of SP

FRIO-Temp® Thermometers are used to verify temperatures in freezers, refrigerators, incubators and ovens with traceability to NIST, DKD/PTB and most standards through ILAC.

Supplier: WORLD PRECISION INSTRUMENTS LLC

When precise temperature measurements are required, WPI can provide you with a very accurate monitor and thermocouple microprobes. WPI monitors have both resolution and accuracy of 0.1 °C in the 0 to 50 °C range and are traceable to NIST standards, whereas other competitive electronic thermometers have an accuracy that is usually to 0.5 °C or worse. Furthermore, all our type T clinical probes are guaranteed accurate to 0.1 °C, due to our stringent wire standards. These are five times more accurate than competitive probes made with regular 'Special Limits' wire.

Supplier: 3M Healthcare

3M™ Under Sink Full Flow Water Filter System 3MFF100 is one of several options in a complete product portfolio delivering cleaner, clearer drinking water. This under sink filtration system is NSF listed to reduce particulate, chlorine taste a select VOCs such as benzene, p-Dichlorobenzene and toxaphene. This system connects to the primary kitchen or bath water faucet.

Supplier: 3M Healthcare

3M™ Aqua–Pure™ Under Sink Dedicated Faucet Replacement Water Filter Cartridge C–LC to reduce sediment, chlorine taste and odor to provide cleaner, clearer, great tasting drinking water at home. Part of the AP Easy LC and LC Cooler systems, it installs with an easy ¼ twist to remove the old and replace with the new.

Supplier: Bel-Art Products, a Part of SP

FRIO-Temp® Thermometers are used to verify temperatures in freezers, refrigerators, incubators and ovens with traceability to NIST, DKD/PTB and most standards through ILAC.

Supplier: CYTOART, INC. MS

A specialized rabbit monoclonal antibody with high specificity for binding to the extracellular domain of the GC33 scFv within Chimeric Antigen Receptors (CARs). The GC33 scFv fragment is derived from a mouse monoclonal antibody that targets Glypican-3 (GPC3), a cell surface antigen implicated in hepatocellular carcinoma (HCC). GPC3's elevated presence in liver cancer is linked to tumor progression and metastasis, underscoring its significance as a biomarker and therapeutic target. Ongoing clinical trials are exploring the potential of GPC3-targeted CAR-T cells in treating HCC.

Supplier: CYTOART, INC. MS

1A3 specifically binds to the scFv region of a B-cell maturation antigen (BCMA) specific mouse monoclonal antibody (mAb, clone C11D5.3). BCMA is a protein that has been reported to be selectively expressed by B-lineage cells including multiple myeloma cells1 and restrictively expressed in both normal and malignant plasma cells at high levels2. The scFv region of C11D5.3 has been used to develop BCMA-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: CYTOART, INC. MS

This antibody reacts with cell membrane-expressed CARs of varying specificity containing a G4S linker within the scFv of the extracellular domain. The poly-Glycine-Serine (G4S) linker is a kind of synthetic peptide linker sequence that is flexible and unstructured. It is frequently used to link the variable heavy (VH) domain and the variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that have an extracellular domain scFv for recognizing target antigens. The linker is made up of a core pentapeptide sequence, Gly-Gly-Gly-Gly-Ser.

Supplier: Desco

Transparent, metal-out static shielding bags are designed to provide static safe packaging for the shipment and/or storage of ESD sensitive items, including outside ESD protected areas. Bags are printed with an ESD protective symbol and a lot code for traceability. Open Top and ZipTop styles are available. The bags are heat sealable.

Supplier: CYTOART, INC. MS

1A3 specifically binds to the scFv region of a B-cell maturation antigen (BCMA) specific mouse monoclonal antibody (mAb, clone C11D5.3). BCMA is a protein that has been reported to be selectively expressed by B-lineage cells including multiple myeloma cells1 and restrictively expressed in both normal and malignant plasma cells at high levels2. The scFv region of C11D5.3 has been used to develop BCMA-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.

Supplier: FUJIFILM IRVINE SCIENTIFIC WAKO CHE

The LBIS™ Mouse OVA-IgE ELISA Kit by FUJIFILM Wako enables quantitative measurement of mouse anti-OVA-IgE antibody titers in serum or plasma.

Supplier: CYTOART, INC. MS

This antibody reacts with cell membrane-expressed CARs of varying specificity containing a G4S linker within the scFv of the extracellular domain. The poly-Glycine-Serine (G4S) linker is a kind of synthetic peptide linker sequence that is flexible and unstructured. It is frequently used to link the variable heavy (VH) domain and the variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that have an extracellular domain scFv for recognizing target antigens. The linker is made up of a core pentapeptide sequence, Gly-Gly-Gly-Gly-Ser.

Supplier: Antyila Scientific

Choose a heater, then blocks to suit your application needs.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human angiotensin-converting enzyme 2 (ACE2).

Supplier: Mettler Toledo

The next generation of Micro-Analytical weighing has arrived. The XPR micro-analytical balances provide ultimate accuracy and quality assurance functions that are second to none.

Supplier: Ward's Science

Learn about biplastics and how their composition affects their physical properties.

Supplier: United Scientific Supplies

Precision apparatus uses sound waves to clearly illustrate the often poorly understood phase and group velocity concepts

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry GP protein of Bombali Ebolavirus (GenBank: YP_009513277.1).

Supplier: Vileda Professional - FHP

SpillEx Pads are the ideal solution for spill pickup or equipment leaking, makes free from the risk of cross contamination.

Supplier: COMMUNITY LEARNING LLC SE

A study in forensic science.

Supplier: ARBOR ASSAYS MS

The Hydrogen Peroxide Colorimetric Detection Kit from Arbor Assays provides sensitive quantification of hydrogen peroxide (H₂O₂) in urine, buffer systems, and tissue culture media (TCM). The assay uses an HRP-catalyzed reaction to produce a colored product measured at 560 nm, with a detection range of 3.125 to 100 µM and sensitivity down to 1.83 µM. The simple 30-minute workflow allows rapid assessment of oxidative stress markers in biological or experimental systems. With a robust and easy-to-use protocol, this kit is ideal for research in redox biology, oxidative stress, and cell signaling pathways.

Supplier: ARBOR ASSAYS MS

The Galactose Colorimetric Detection Kit from Arbor Assays provides sensitive and specific quantification of galactose in serum, plasma, tissue culture media, and buffers. Utilizing a galactose oxidase reaction coupled to HRP-mediated color development, the assay detects galactose concentrations down to 0.493 mg/dL over a 0.781 to 25 mg/dL range. With a fast, 30-minute protocol and low sample volume requirement, the kit is ideal for studies of metabolic regulation, galactosemia, glycolipid turnover, and nutritional biochemistry across multiple research models.