1082 Results for: "Test Lead"

Supplier: Southern Biotechnology

CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.

Supplier: Southern Biotechnology

CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.

Supplier: Southern Biotechnology

CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.

Supplier: Southern Biotechnology

CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3ε is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. 500-A2 recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex of mouse strains tested.

Supplier: Boster Biological Technology

Polyclonal antibody for p27/CDKN1B detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. p27/CDKN1B information: Molecular Weight: 22073 MW; Subcellular Localization: Nucleus. Cytoplasm. Endosome . Nuclear and cytoplasmic in quiescent cells. AKT- or RSK- mediated phosphorylation on Thr-198, binds 14-3-3, translocates to the cytoplasm and promotes cell cycle progression. Mitogen- activated UHMK1 phosphorylation on Ser-10 also results in translocation to the cytoplasm and cell cycle progression. Phosphorylation on Ser-10 facilitates nuclear export. Translocates to the nucleus on phosphorylation of Tyr-88 and Tyr-89. Colocalizes at the endosome with SNX6; this leads to lysosomal degradation (By similarity); Tissue Specificity: Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney.

Supplier: Boster Biological Technology

Polyclonal antibody for CD104/ITGB4 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. CD104/ITGB4 information: Molecular Weight: 202167 MW; Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction, hemidesmosome. Colocalizes with DST at the leading edge of migrating keratinocytes; Tissue Specificity: Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.

Supplier: Bioss

Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into hiding,? the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.

Supplier: Bioss

Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into hiding,? the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.

Supplier: Enzo Life Sciences

8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging and neurodegenerative conditions, such as Alzheimer's disease. 8OHdG has become increasing popular as a sensitive, stable and integral marker of oxidative damage in cellular DNA. Biomonitoring in humans has demonstrated that 8OHdG can be excreted in the urine and that a significant increase is caused by exposure to tobacco smoke and ionizing radiation. Because 8OHdG is so well correlated with oxidative stress and damage to DNA, which leads to degenerative disease states, the development of an antibody that can be used to study DNA damage has numerous applications. In addition to the direct study of DNA damage within cells, this antibody has applications in the development of immunoassays that can monitor 8OHdG excretion in the urine and serve as a biomarker of oxidative stress. Industrial uses may extend to the dietary supplement manufacturers, who could benefit from an immunoassay that could be used to test the effectiveness of antioxidants and other nutraceuticals.

Supplier: Boster Biological Technology

Polyclonal antibody for TIGHT JUNCTION PROTEIN 1/TJP1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. TIGHT JUNCTION PROTEIN 1/TJP1 information: Molecular Weight: 195459 MW; Subcellular Localization: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, tight junction. Cell junction. Cell junction, gap junction. Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact. Detected at the leading edge of migrating and wounded cells; Tissue Specificity: The alpha-containing isoform is found in most epithelial cell junctions. The short isoform is found both in endothelial cells and the highly specialized epithelial junctions of renal glomeruli and Sertoli cells of the seminiferous tubules.

Supplier: SPEX CERTIPREP LLC

Pesticides, PCBs and Herbicides

The EPA is tasked with the monitoring of environmental systems as they pertain to contamination and human health. The methods issued by the EPA are created to respond to specific toxins or persistent organic pollutants (POPs) found in environmental samples such as soil, source water, drinking water, and waste. In particular, pollutants such as polychlorinated biphenyls (PCBs), which were in widespread industrial use up until their restriction, are of concern due to their stable and persistent nature in the environment. Another group of chemicals of high concern is the hundreds of commercial pesticides and herbicides in use in the world today. Pesticides, from algaecides to virucides, are used in large quantities in industrial and private agriculture. The concern over human pesticide exposure over the past few decades has led to extensive monitoring of these pesticides. It has been reported that over 98% of insecticides and 95% of herbicides affect areas other than their intended target product. It is essential that monitoring agencies have accurate standard mixes to measure the pesticide levels in the environment.

Many new pesticides are now being tested using highly sensitive LC/MS techniques, in addition to traditional GC techniques, to determine minute amounts of residue in environmental samples and food products.

At SPEX CertiPrep, we facilitate ease of monitoring and testing of pesticides by creating pesticide test mixes to suit your monitoring needs. SPEX CertiPrep is the leader in offering pesticide standards designed to work within EPA, AOAC and FDA analytical testing methods using all of the leading analytical techniques: LC, LC/MS, GC, and GC/MS. Many pesticide standard mixes are readily available in our catalog along with a large list of single pesticide standards. In addition, custom pesticide mixes can be made to your specifications to create a mix that meets your needs.

US EPA Method 508 is an analytical method for the monitoring of organochlorine pesticides and PCBs in drinking water and ground water by GC/ECD

Supplier: SPEX CERTIPREP LLC

Pesticides, PCBs and Herbicides

The EPA is tasked with the monitoring of environmental systems as they pertain to contamination and human health. The methods issued by the EPA are created to respond to specific toxins or persistent organic pollutants (POPs) found in environmental samples such as soil, source water, drinking water, and waste. In particular, pollutants such as polychlorinated biphenyls (PCBs), which were in widespread industrial use up until their restriction, are of concern due to their stable and persistent nature in the environment. Another group of chemicals of high concern is the hundreds of commercial pesticides and herbicides in use in the world today. Pesticides, from algaecides to virucides, are used in large quantities in industrial and private agriculture. The concern over human pesticide exposure over the past few decades has led to extensive monitoring of these pesticides. It has been reported that over 98% of insecticides and 95% of herbicides affect areas other than their intended target product. It is essential that monitoring agencies have accurate standard mixes to measure the pesticide levels in the environment.

Many new pesticides are now being tested using highly sensitive LC/MS techniques, in addition to traditional GC techniques, to determine minute amounts of residue in environmental samples and food products.

At SPEX CertiPrep, we facilitate ease of monitoring and testing of pesticides by creating pesticide test mixes to suit your monitoring needs. SPEX CertiPrep is the leader in offering pesticide standards designed to work within EPA, AOAC and FDA analytical testing methods using all of the leading analytical techniques: LC, LC/MS, GC, and GC/MS. Many pesticide standard mixes are readily available in our catalog along with a large list of single pesticide standards. In addition, custom pesticide mixes can be made to your specifications to create a mix that meets your needs.

US EPA Method 8082 is an analytical method for the monitoring of PCBs in environmental samples by GC/ECD or GC/ELCD

Supplier: SPEX CERTIPREP LLC

Pesticides, PCBs and Herbicides

The EPA is tasked with the monitoring of environmental systems as they pertain to contamination and human health. The methods issued by the EPA are created to respond to specific toxins or persistent organic pollutants (POPs) found in environmental samples such as soil, source water, drinking water, and waste. In particular, pollutants such as polychlorinated biphenyls (PCBs), which were in widespread industrial use up until their restriction, are of concern due to their stable and persistent nature in the environment. Another group of chemicals of high concern is the hundreds of commercial pesticides and herbicides in use in the world today. Pesticides, from algaecides to virucides, are used in large quantities in industrial and private agriculture. The concern over human pesticide exposure over the past few decades has led to extensive monitoring of these pesticides. It has been reported that over 98% of insecticides and 95% of herbicides affect areas other than their intended target product. It is essential that monitoring agencies have accurate standard mixes to measure the pesticide levels in the environment.

Many new pesticides are now being tested using highly sensitive LC/MS techniques, in addition to traditional GC techniques, to determine minute amounts of residue in environmental samples and food products.

At SPEX CertiPrep, we facilitate ease of monitoring and testing of pesticides by creating pesticide test mixes to suit your monitoring needs. SPEX CertiPrep is the leader in offering pesticide standards designed to work within EPA, AOAC and FDA analytical testing methods using all of the leading analytical techniques: LC, LC/MS, GC, and GC/MS. Many pesticide standard mixes are readily available in our catalog along with a large list of single pesticide standards. In addition, custom pesticide mixes can be made to your specifications to create a mix that meets your needs.

US EPA Method 531 is an analytical method for the monitoring of n-methylcarbamoyloximes and n-methylcarbamates in drinking water and ground water by HPLC and a fluorescence detector

Supplier: Boster Biological Technology

Polyclonal antibody for FKHR/FOXO1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. FKHR/FOXO1 information: Molecular Weight: 69662 MW; Subcellular Localization: Cytoplasm . Nucleus . Shuttles between the cytoplasm and nucleus. Largely nuclear in unstimulated cells. In osteoblasts, colocalizes with ATF4 and RUNX2 in the nucleus (By similarity). Insulin-induced phosphorylation at Ser-256 by PKB/AKT1 leads, via stimulation of Thr-24 phosphorylation, to binding of 14-3-3 proteins and nuclear export to the cytoplasm where it is degraded by the ubiquitin-proteosomal pathway. Phosphorylation at Ser-249 by CDK1 disrupts binding of 14-3-3 proteins and promotes nuclear accumulation. Phosphorylation by NLK results in nuclear export. Translocates to the nucleus upon oxidative stress-induced phosphorylation at Ser-212 by STK4/MST1. SGK1-mediated phosphorylation also results in nuclear translocation. Retained in the nucleus under stress stimuli including oxidative stress, nutrient deprivation or nitric oxide. Retained in the nucleus on methylation; Tissue Specificity: Ubiquitous.

Supplier: Rockland Immunochemical

BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.

Supplier: Rockland Immunochemical

BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.

Supplier: Prosci

BRSK1 Antibody: BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.

Supplier: Prosci

BRSK1 Antibody: BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.

Supplier: Prosci

BRSK1 Antibody: BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.

Supplier: Prosci

BRSK1 Antibody: BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.

Supplier: Rockland Immunochemical

Variable Lipoprotein Surface-Exposed protein, or VlsE, is a lipoprotein on the surface of the Lyme Disease spirochete Borrelia burgdorferi, detectable during all its life stages. VlsE has variable regions (VRs) and invariable regions (IRs). Some IRs are anchored in the outer membrane of the bacteria and some are antigens exposed on the membrane surface. Replacement of the VR by Borrelia within days of being transferred to a mammalian host presents new surface antigens to the host immune system, and helps Borrelia avoid a strong reaction by host immune systems. The VlsE is apparently not modified as much in the tick or in the rodent vector, when compared to in the mammal host. Several putative envelope proteins of B. burgdorferi appear to be expressed only in the infected mammalian host. The VRs are antigenic, irregularly shaped loops on the bacterial surface which may help to hide both membrane-incorporated and surface portions of adjacent proteins from immune cells. These VR loops are coded by antigenic cassettes. The protein loops can therefore be switched in or out of the protein, or different type loops traded. In B. burgdorferi there seem to be at least fifteen different VlsE cassettes that can insert into any of the variable regions of VlsE, allowing it to appear as millions of different antigens. Similar, but smaller, systems also operate for OSP-A, OSP-B, OSP-C, and other proteins. One IR region, C6, of the VlsE protein, consistently stimulates a strong immune response. Its presentation may be a decoy that misdirects the immune system from less protected sites by causing competion for binding antibodies. The bound antibodies are thus not available for binding important therapeutic proteins. This may help Borrelia to enter T-cells, leading to their destruction. Because IR6 is invariable and found in all life stages of B. burgdorferi, it has been used in an ELISA diagnostic test for early IgM of Lyme Disease.

Supplier: Hach

They are used for determining lead by the LeadTrak™ Fast Column Extraction method.

Supplier: MilliporeSigma

For the Digestion of Lead, Cadmium, Iron, Copper, Nickel, Phosphorus (Total) and Zinc

Supplier: MilliporeSigma

For the Digestion of Lead, Cadmium, Iron, Copper, Nickel, Phosphorus (Total) and Zinc

Supplier: FUJIFILM IRVINE SCIENTIFIC WAKO CHE

The SLP-HS Single Reagent Set II is able to detect both peptidoglycan (PG) and (1-3)-β-D-glucan (BDG). The product uses a self-defense mechanism of silkworm Bombyx mori which leads to a color change by building a black melanin pigment in the presence of microbial contamination.

Supplier: Precision Laboratories

Available in 8 books of 25 sheets, or vials containing 100 sheets.

Supplier: SCIENCE TAKE-OUT, LLC

Explore how climate change may lead to health problems.

Supplier: PerkinElmer

This lamp is designed for use with and tested on spectrometers to assure compatibility and the highest performance.

Supplier: Genetex

The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a andC3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.

Supplier: Clarity Diagnostics

Test strips for urinalysis testing of various parameters.