1594 Results for: "Other Essentials"

Supplier: Anaspec

HiLyte™ Fluor 647 acid, SE (Ex/Em=647 nm/679 nm) is an excellent fluorescent labeling dye that generates the protein conjugates that are slightly red-shifted compared to those of Cy® 5 dyes, resulting in an optimal match to filters designed for Cy®5 dyes

Supplier: Anaspec

HiLyte™ Fluor 647 acid, SE (Ex/Em=647 nm/ 679 nm) is an excellent fluorescent labeling dye that generates the protein conjugates that are slightly red-shifted compared to those of Cy® 5 dyes, resulting in an optimal match to filters designed for Cy®5 dyes

Supplier: Cloud-Clone

This is a APOB100 recombinant protein (prokaryotic), Human is sequencing from His3365~Glu3548 with 90 to 100% purity. LyopH ilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Genetex

Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3. Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. The Dnmt3 family members, Dnmt3a and Dnmt3b, are strongly expressed in ES cells but their expression is down regulated in differentiating ES cells and is low in adult somatic tissue. Dnmt1 co-purifies with the retinoblastoma (Rb) tumour suppressor gene product, E2F1, and HDAC1. Dnmt1 also cooperates with Rb to repress transcription from promoters containing E2Fbinding sites suggesting a link between DNA methylation, histone deacetylase and sequence-specific DNA binding activity, as well as a growth-regulatory pathway that is disrupted in nearly all cancer cells.

Supplier: Cloud-Clone

This is a E2 conjugated BSA, General species is sequencing from C18H24O2 with 90 to 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.

Supplier: Cayman Chemical Company

For the measurement of SOD activity from plasma, serum, tissue homogenates, and cell lysates.

Supplier: Genetex

Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. In contrast, LIN28A down-regulation in neural stem cells by miR-125, allows the processing of pre-let-7. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation.

Supplier: Abcam

The DNA Isolation Kit-Urine (ab156899) is a complete set of essential components which enables the experimenter to efficiently isolate DNA from urine.

Supplier: Genetex

Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3. Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. The Dnmt3 family members, Dnmt3a and Dnmt3b, are strongly expressed in ES cells but their expression is down regulated in differentiating ES cells and is low in adult somatic tissue. Dnmt 1 co-purifies with the retinoblastoma (Rb) tumour suppressor gene product, E2F1, and HDAC1. Dnmt 1 also cooperates with Rb to repress transcription from promoters containing E2F binding sites suggesting a link between DNA methylation, histone deacetylase and sequence-specific DNA binding activity, as well as a growth-regulatory pathway that is disrupted in nearly all cancer cells.

Supplier: Genetex

Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins (Histone 2A, 3, 4), IL enhancer binding factor, nuclear factors (NF45, 90, ILF3, Nucleolin, STAT1, Poly(A) binding protein II), cell cycle proteins (phosphoprotein phosphatase 2A), signal transduction proteins (FGF2, Fibrillarin, FN, INFAR1, Jak, MBP, Src adaptor Sam68), apoptosis proteins (FADD, ICE like protease), and viral proteins (Hepatitis C NS3 RNA Helicase, HIV TAR). The mammalian PRMT family currently consists of 5 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all five PRMT members have been developed. These antibodies can be utilized to explore arginine methylation and its regulatory functions.

Supplier: Rockland Immunochemical

Anti IL-10 Antibody recognizes IL-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), that is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. IL-10 is produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kB activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract and indeed patients with Crohn's disease react favorably towards treatment with bacteria producing recombinant interleukin 10, showing the importance of interleukin 10 for counteracting excessive immunity in the human body. Anti-IL-10 cytokine antibody is ideal for investigators involved Immunology and Signal Transduction research.

Supplier: Zymo Research

Yeast lytic enzyme used for digestion of yeast and fungal cell walls.

Supplier: HANNA INSTRUMENTS

This is a chemical test kit that measures dissolved oxygen by modified Winkler titration. The HI3810 is supplied complete with all of the reagents and equipment necessary to perform approximately 110 tests.

Supplier: WALLCUR, LLC.

Prelabeled Vials For Convenience

Supplier: Boster Biological Technology

Rabbit IgG polyclonal antibody for Transcription factor SOX-1(SOX1) detection. Tested with WB in Human;Mouse;Rat.

Supplier: Rockland Immunochemical

Human BDNF AccuSignal ELISA Kit

Supplier: Biotium

EMI1 Monoclonal antibody, Clone: EMI1/1176, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF405S, Immunogen: Recom fragment of human EMI1 protein, Synonyms: Early Mitotic Inhibitor-1 (EMI1), FBX5, Fbxo31, Application: IF, IHC, Size: 100uL

Supplier: Anaspec

HiLyte™ Fluor 488, SE is an excellent amine-reactive fluorescent labeling dye for generating protein conjugates. The spectrum of HiLyte™ Fluor488 is similar to fluorescein (FITC), resulting in an optimal match to filters designed for fluorescein.

Supplier: Anaspec

SensoLyte® Luminescent Alkaline Phosphatase Assay Kit provides highly sensitive chemiluminescent substrate to quantify alkaline phosphatase activity in solutions, in cell extracts, in live cells.

Supplier: Rockland Immunochemical

Mouse Cripto - TDGF1 AccuSignal ELISA Kit

Supplier: Cloud-Clone

Polyclonal Antibody to Coagulation Factor V (F5), derived from recombinant F5 (Cys1894~Gly2047), is reactive with Human/Bovine.

Supplier: Rockland Immunochemical

Human Prolactin AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Human C-MET - HGFR AccuSignal ELISA Kit

Supplier: AMPLYUS LLC

Examine the primary, secondary, and tertiary structures of fluorescent proteins.

Supplier: Cloud-Clone

Polyclonal Antibody to Coagulation Factor V (F5), derived from recombinant F5(Asp1863~Arg2161), is reactive with Human/Mouse.

Supplier: Cloud-Clone

Polyclonal Antibody to Microtubule Associated Protein 2 (MAP2), derived from recombinant MAP2 (Leu727~Asp985), is reactive with Human/Mouse/Rat/Pig.

Supplier: Cloud-Clone

Polyclonal Antibody to Estradiol (E2), derived from OVA conjugated E2, is reactive with General species.

Supplier: Boster Biological Technology

Rabbit IgG polyclonal antibody for NLR family CARD domain-containing protein 4(NLRC4) detection. Tested with WB in Human;Mouse;Rat.

Supplier: Biotium

FOXP3 Monoclonal antibody, Clone: 3G3, Host: Mouse, Species reactivity: Mouse, Monkey, Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Full-length His-tagged mouse FOXP3 protein, Application: Immunofluorescence, Flow cytometry, Size: 500 uL

Supplier: Biotium

WT1 (Wilm's Tumor 1), Monoclonal antibody, Clone: WT1/857 + 6F-H2, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recombinant protein with residues 1-181 human WT1, Synonym: WT1, Size: 500uL