1142 Results for: "NMR"

Supplier: Adipogen

Reversible cell permeable p300/CBP histone acetyltransferase (HAT) inhibitor. Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (10%). Cell growth inhibitor in melanoma and non-small-cell-lung (NSCL) human cancer cell lines.

Supplier: Adipogen

Activated ester of ruthenium complex for acylation of amino acid side chain amines. This label is perfectly suitable for 1D- or 2D-protein gel staining. A simple pre-electrophoresis procedure provides a sensitivity better than SYPRO Ruby and a similar dynamic range. In contrast to SYPRO Ruby, this staining exhibits a logarithmic dependency on the amount of protein.

Supplier: Adipogen

Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8.8 µM). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Blocks peptide substrate binding. HIV-1 RT polymerase inhibitor (IC50 = 5.0 µM).

Supplier: Adipogen

Potent and selective inhibitor of CDKs. More potent than olomoucine. Inhibits CDK1/cyclin B kinase (IC50 = 450 nM), CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM). Inhibits M phase promoting factor (MPF) kinase activity. Arrests human fibroblasts in G1 phase. Antitumor compound. Activates the mitogen-activated protein kinase pathway. Targets both the p53 and NF-kappaB pathways[10]. Has effects on calcium channel gating. Prevents DNA damage-induced cyclin A1 upregulation. Apoptosis inducer. As CYC202 in phase I clinical trials. Reviews.

Supplier: Enzo Life Sciences

Organoselenium compound

Supplier: Adipogen

Derivative of Aphidicolin (BVT-0307) http://www.adipogen.com/bvt-0307/-aphidicolin.html. Mycotoxin. So far no comparison to aphidicolin's biological activity (DNA polymerase alpha antiviral and antitumor activity) has been performed.

Supplier: Adipogen

Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor.

Supplier: Adipogen

Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon http://www.adipogen.com/ag-cr1-0154/adiporon.html . Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.

Supplier: Adipogen

Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric evaluation of pH (F400/440). No esterases are involved, therefore no toxic by-products occur. Long-term stable; is barely metabolized. Fluorescence co-localizes with LysoTracker® Red DND-99. (LysoTracker® is a registered trademark of Molecular Probes, Inc.)

Supplier: Adipogen

Cell permeable highly active Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist.

Supplier: TCI America

[NMR Shift Reagent] CAS Number: 15522-71-1 MDL Number: MFCD00000019 Molecular Formula: C33H57EuO6 Molecular Weight: 701.78 Purity/Analysis Method: 95.0% (T) Form: Crystal Color: Pale Yellow Melting point (°C): 190

Supplier: Adipogen

Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.

Supplier: Adipogen

Fluorogenic substrate used to measure sensitively enzymatic neuraminidase activity in fluorometric assays in mammalian and viral sources. Neuraminidase is catalyzed by the hydrolysation to form N-acetylneuraminic acid and the blue fluorescent soluble compound 4-Methylumbelliferone, which can be detected fluorometrically. Spectral data: lambdaex 315 nm| lambdaem 374 nm (pH.7.0) or lambdaex 365 nm| lambdaem 445 nm (after cleavage by neuraminidase). Used for fluorescent staining of sialidases in PAGE.

Supplier: Enzo Life Sciences

PTP inhibitor, PTEN Inhibitor

Supplier: Ward's

Accessories for Digital Dry Bath Block Heaters

Supplier: TCI America

CAS Number: 5394-63-8 MDL Number: MFCD00040468 Molecular Formula: C7H10O3 Molecular Weight: 142.15 Purity/Analysis Method: 95.0% (NMR) Form: Liquid Color: Yellow Boiling point (°C): 77 Flash Point (°C): 86 Specific Gravity (20/20): 1.08

Supplier: Enzo Life Sciences

Serotonin receptor activator

Supplier: Enzo Life Sciences

Supplier: Enzo Life Sciences

Potent antioxidant

Supplier: Adipogen

Cell permeable, highly potent inhibitor of gamma-secretase (IC50 = 0.06 nM).

Supplier: Enzo Life Sciences

mGluR5 antagonist.

Supplier: Adipogen

Protein kinase C (PKC) inhibitor. Binds with reversed orientation to protein kinase A (PKA).

Supplier: Enzo Life Sciences

Potent and selective phosphoinositide 3-kinase (PI(3)K) p110γ inhibitor shown to be selective for class IB PI(3)K-mediated cellular effects.

Supplier: Chem-Impex International

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Supplier: Enzo Life Sciences

Phytoestrogen.

Supplier: Adipogen

Pyridomycin is a Cyclodepsipeptide antibiotic.

Supplier: Enzo Life Sciences

Nitric oxide (NO) donor.

Supplier: Adipogen

Albocycline is a 14-membered macrolide antibiotic without sugar moieties.

Supplier: Indofine Chemical Company

Rare Organics & BioChemicals 106391-87-1 1gm BOC-D-Val-ol 203.3 Room temperature.

Supplier: Adipogen

Selective N- and P/Q-type Ca2+-channel agonist. These Ca2+-channels regulate transmitter release in synapses. Potential lead compound for a variety of disorders that result in neuromuscular weakness.