1142 Results for: "NMR"

Supplier: Chem-Impex International

N-Methylbenzylamine (CAS 103-67-3) is a versatile organic compound used in pharmaceuticals, agrochemicals, and specialty chemicals. Its unique properties make it ideal for organic synthesis, surfactants, and corrosion inhibitors, providing essential solutions for researchers and industry professionals.

Supplier: Adipogen

Nucleoside antibiotic. Antitumor compound. Xanthosine monophosphate (XMP) aminase inhibitor. RNA synthesis inhibitor. Specific GMP synthase inhibitor. Reduces intracellular GTP levels.

Supplier: Adipogen

Specific cell permeable SIRT1 (sirtuin 1) inhibitor. Senescence-like growth arrest inducer. Platelet aggregation inhibitor. Apoptosis inducer.

Supplier: Chem-Impex International

3'-Benzyloxyacetophenone is a key organic compound used in pharmaceuticals and fine chemicals. Its unique structure allows for versatile applications in drug synthesis and photochemical processes, making it essential for researchers and industry professionals.

Supplier: Adipogen

beta-Naphthocyclinone is an Isochromane quinone antibiotic.

Supplier: Adipogen

Sonic hedgehog (Shh) signaling pathway modulator. Cell permeable potent smoothened (Smo) antagonist. Inhibits wt and oncogenic Smo. SAG activity (Prod. Nr. AG-CR1-3506) inhibitor. Gli1 reporter gene expression inhibitor. Suppresses the Shh-dependent translocation of Smo to the primary cilium. Potential tumor growth blocker.

Supplier: Enzo Life Sciences

Inhibitor of human CDK1 (IC50=4nM), CDK2/cyclin A (IC50=70nM), Cdc2/cyclin B, CDK2/cyclin E (IC50=35nM), CDK4/cyclin D1 (IC50=850nM) as well as CDK5/p35 (IC50=75nM). More membrane permeable than purvalanol B.

Supplier: Adipogen

Salt for the generation of cationic transition metal complexes.

Supplier: Adipogen

Highly selective and potent non-peptide delta-opioid receptor agonist. Mediates downregulation of the delta-opioid receptor. Shows antidepressant-like effects. Modulates voltage-dependent sodium channels. Antinociceptive. Activates ATP-sensitive K+ channels. Enhances amphetamine-mediated dopamine efflux.

Supplier: Adipogen

Potent and subtype-selective (1'000-fold) PPARgamma agonist. Angiogenesis inhibitor. Apoptosis inhibitor. Anti-inflammatory. Anti-hyperglycemic and anti-hyperlipidemic agent. Antidiabetic. The glucose-lowering effect in rats is 100-fold more potent than that of troglitazone.

Supplier: Adipogen

Potent CDK1/cyclin B (IC50 = 9.5 nM) and CDK2/cyclin A3 (IC50 = 5.4 nM) inhibitor. 1'000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1.6 µM), DYRK1A (IC50 = 0.9 µM), PDK1 (IC50 = 0.8 µM) and ROCK-II (IC50 = 0.6 µM). Inhibits cell growth.

Supplier: SP Industries

High quality 5 mm NMR spinner turbines exceed Bruker® specifications.

Supplier: Adipogen

Nitric oxide (NO) independent, superoxide-sensitive soluble guanylyl cyclase (sGC) activator. Induces concentration-dependent increase in cGMP levels. Inhibits platelet adhesion to collagen. Thombosis inhibitor. Non-specific phosphodiesterase inhibitor. Na+ channel blocker. Anticancer compound. HIF-alpha inhibitor. Blocks angiogenesis. Tumor growth inhibitor. Apoptosis inducer. NK cell differentiation enhancer. TRAIL sensitizer.

Supplier: Enzo Life Sciences

SIRT inhibitor

Supplier: Enzo Life Sciences

GTPase inhibitor

Supplier: Adipogen

Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competetive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.

Supplier: Adipogen

Potent cell permeable and selective inhibitor of yeast NAD+-dependent histone deacetylase (HDAC) Sir2p. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket. Shown to have diverse effects also in mammalian cells.

Supplier: Enzo Life Sciences

GSK-3beta inhibitor

Supplier: Adipogen

Synthetic. Originally isolated from the marine sponge Angelas mauritianus. Immunostimulant. Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells. Protects against LPS-induced shock. Potent antitumor compound.

Supplier: Adipogen

Potent and selective FXR agonist (EC50= 99nM). Induces SHP in HSCs to suppress TIMP-1 expression. Apoptosis inducer. Protects against liver fibrosis development in rat in vivo. Displays anticholeretic activity in rat in vivo. Promotes preadipocyte differentiation. Regulates adipogenesis and insulin signaling in vivo. Inhibits vascular smooth muscle cell inflammation and migration.

Supplier: Adipogen

Cytotoxic and anti-inflammatory compound (weak). Antioxidant. Lipid peroxidation inhibitor. Free radical scavenger. Inhibitor of myeloperoxidase activity. Hypoglycemic. Decreases blood glucose levels in diabetic and normal rats. Insulinomimetic. Modulates glucose homeostasis. Decreases blood glucose levels and stimulates glucose uptake in muscle. Inhibits GLUT4 mediated glucose uptake in differentiated 3T3-L1 cells. Improves insulin resistance by the activation of the classical insulin transduction pathway. Increases adiponectin secretion in 3T3-L1 adipocytes. Antinoniceptive. May have antidyslipidemic activity.

Supplier: Adipogen

Nuclear protein pirin inhibitor. Inhibits the interaction between Bcl3 oncoprotein and the nuclear protein pirin. Melanoma cell migration inhibitor.

Supplier: Adipogen

Cell permeable gamma-secretase inhibitor (IC50 = 115 nM for total beta-amyloid, IC50 = 200 nM for beta-amyloid 1-42). Reduces Abeta levels in vivo. Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD). Does not inhibit persenilinase. Notch processing inhibitor. Enhances neuronal differentiation independent of sonic hedgehog (Shh) signaling. CDK5 activity inhibitor. Apoptosis enhancer.

Supplier: Enzo Life Sciences

gamma-Secretase inhibitor

Supplier: Adipogen

Enhancer of myocardial regenerative repair by stem cells. Potent inducer of Nkx2.5 and a subset of other cardiac markers, including myocardin, and sarcomeric-tropomyosin (SalphaTM) in a variety of different stem/progenitor cells.

Supplier: Adipogen

Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor. Apoptosis inducer. Potent glycogen synthase kinase (GSK-3alpha/beta) inhibitor.

Supplier: Enzo Life Sciences

Organoselenium compound

Supplier: TCI America

[NMR Shift Reagent] CAS Number: 15492-48-5 MDL Number: MFCD00000027 Molecular Formula: C33H57O6Pr Molecular Weight: 690.72 Form: Crystal Color: Slightly Pale Yellow Melting point (°C): 220

Supplier: Adipogen

Dynamin-1, -2 (DNM1, DNM2) and Dynamin-related protein 1 (DRP1) inhibitor. Endocytosis inhibitor. Viral infection inhibitor. Destabilizes actin filaments. Inhibits entry of Trypanosoma into macrophages. Inhibitor of mitophagy. Inhibitor of hepatocyte lipophagy

Supplier: Adipogen

Activated ester of ruthenium complex for acylation of amino acid side chain amines. This label is perfectly suitable for 1D- or 2D-protein gel staining. A simple pre-electrophoresis procedure provides a sensitivity better than SYPRO Ruby and a similar dynamic range. In contrast to SYPRO Ruby, this staining exhibits a logarithmic dependency on the amount of protein.