1142 Results for: "NMR"

Supplier: Adipogen

Poly(ADP-ribose) polymerase (PARP) inhibitor.

Supplier: Adipogen

Fluorescent indicator.

Supplier: Adipogen

Natural cytochalasin derivative. Antiviral. Inhibitor of HIV-1 protease. Antifungal activity.

Supplier: Adipogen

N-Heptanoyl-L-homoserine lactone (C7-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The diverse applications of this molecule include regulation of virulence, infection prevention and septicemia in fish.

Supplier: Adipogen

alpha-Glucosidase inhibitor. Inhibitor of glycoprotein processing. Strong glycosyltransferase (GTF) inhibitor. Angiogenesis inhibitor. Reduces the size of myocardial infarcts.

Supplier: Adipogen

Potent stimulator of invariant natural killer T (iNKT) cells. Induces strong antitumor immunity through a nitric oxide (NO) and TNF-alpha dependent mechansim, different compared to the IFN-gamma dependent mechanism of alpha-GalCer (AG-CN2-0014). Does not induce anergy of iNKT cells.

Supplier: Adipogen

Immunostimulant. Potent stimulator of natural killer T (NKT) cells. Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells. Potent antitumor compound. Stimulates the production of smaller amounts of IFN-gamma than alpha-GalCer, but induces equal or greater IL-4 secretion in mouse models.

Supplier: Enzo Life Sciences

HDAC1 inhibitor

Supplier: Adipogen

Tripyrrolic pigment like prodigiosin. Antimalarial agent. Apoptosis inducer. Anticancer agent with multiple modes of action. Immunosuppressant in non-toxic concentrations. Bone resorption inhibitor. Antiulcer agent.

Supplier: Adipogen

Cytochalasan alkaloid, derivative of chaetoglobosin A . Mycotoxin. Phytotoxin.

Supplier: NANALYSIS CORP.

Warranty Package for 60 MHz Benchtop NMR Spectrometers, Nanalysis

Supplier: Adipogen

N-Ethanoyl-L-homoserine lactone is the shortest alkyl homologue and most polar of a family of mediators of cell to cell interactions in bacterial biofilms. Acylhomoserine lactones have been detected in hundreds of bacterial species. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. N-Ethanoyl-L-homoserine lactone is not found in nature and can serve as a polar negative control for quorum sensing events.

Supplier: Adipogen

Non-cytotoxic melanogenesis inhibitor. Potential depigmentation agent. Tyrosinase-related protein 2 (TRP-2) expression inhibitor, via proteasomal degradation. Inhibits the proliferation of melanocytes and melanoma cells through cell cycle arrest in G1. Moderate skin tumor growth suppressor in vivo.

Supplier: Sino Biological

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine >98% (by TLC, NMR)

Supplier: Adipogen

Mycotoxin Antibacterial against Gram-positive bacteria. Shows antimalarial and antitubercular activity. Anticancer compound. Cytotoxic against several cancer cell lines (pro-apoptotic activity). Active against plant pathogene fungi (e.g. P. oryza, Phyt. infestans). Activator of murine T lymphocytes, NK cells and macrophages.

Supplier: Adipogen

Aza-steroid. Hedgehog signaling inhibitor. Competes with 20(S)-OHC for access to the cysteine-rich domain in Smoothened (Smo). For control compound see 22-NHC (inactive isomer) http://www.adipogen.com/ag-cr1-3524/22-nhc-inactive-isomer.html .

Supplier: Adipogen

N-Hexanoyl-L-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression and affecting cellular metabolism. The diverse applications of this molecule include regulation of virulence in general and in cystic fibrosis, infection prevention, slime and biofilm reduction in commercial agriculture and aquaculture industries, food spoilage prevention and septicemia in fish.

Supplier: Chem-Impex International

N-(3-Formyl-2,5-dimethyl-1H-pyrrol-1-yl)acetamide ≥95% (NMR)

Supplier: Adipogen

N-Decanoyl-L-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include regulation of virulence and exoproteases.

Supplier: Adipogen

Naturally occurring carnitine derivative formed by carnitine acetyltransferase during beta-oxidation of uneven chain fatty acids, with high affinity for muscular carnitine transferase. Increases cellular carnitine content, allowing free fatty acid transport into the mitochondria. Stimulates energy production in ischaemic muscles by increasing citric acid cycle flux and stimulating pyruvate dehydrogenase activity. Important for mitochondrial metabolism and energy regulation. Regulates the metabolism of both carbohydrates and lipids, leading to an increase of ATP generation. Selectively inhibits in vitro and ex vivo platelet-activating factor (PAF) synthesis from human neutrophils. Antioxidant. Shows free radical scavenging activity. Decreases the expression of inducible nitric oxide synthase (iNOS/NOS II) and NADPH-oxidase 4-mediated reactive oxygen species production in human umbilical vascular endothelial cells. Shows beneficial cardiovascular effects. Improves body weight, food intake, adiposity and insulin resistance in Type 2 diabetes. Stimulates endothelial nitric oxide (eNOS/NOS III) and increased NO production, via AMPK/Src-mediated signaling that leads to activation of PI3 kinase and Akt.

Supplier: Adipogen

Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Rescued the shortened lifespan of db/db mice (AdipoRs KO) on high-fat diet. Reduces expression levels of genes encoding inflammatory cytokines such as TNF-alpha, IL-6 and CCL-2 in WAT of WT mice but not db/db mice.

Supplier: SP Industries

Provides easy sample loading for NMR tubes.

Supplier: Adipogen

Helvolic acid is a steroidal triterpene antibiotic.

Supplier: TCI America

CAS Number: 1795-31-9 MDL Number: MFCD00015588 Molecular Formula: C9H27O3PSi3 Molecular Weight: 298.54 Purity/Analysis Method: 95.0% (NMR) Form: Clear Liquid Color: Colorless Boiling point (°C): 73 Flash Point (°C): 110 Specific Gravity (20/20): 0.89

Supplier: Adipogen

Fluorogenic substrate.

Supplier: Adipogen

N-Dodecanoyl-L-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It is important to note that C12-HSL is distinct from N-3-oxo-dodecanoyl-L-homoserine lactone, which is produced at different times in biofilm development and has different cellular effects.

Supplier: Adipogen

Building block for synthesis. Reagent used for electrophilic phenylation, e.g. of malonates and dithiocarboxylates.

Supplier: Adipogen

Fluorogenic substrates for detecting Baeyer-Villiger monooxygenase.

Supplier: Adipogen

A glycolytic intermediate formed by the isomerization of glucose-6-phosphate.

Supplier: Adipogen

Convenient substitute of o-iodoxybenzoic acid (IBX) as an oxidant. FIBX is safer, has neutral properties behaves as an equivalent to IBX in the oxidation of alcohols to ketones or aldehydes in polar solvents and shows better solubility.